• Non steroidal anti androgen Fluridil/Topilutamide powder cas:260980-89-0
  • Non steroidal anti androgen Fluridil/Topilutamide powder cas:260980-89-0
  • Non steroidal anti androgen Fluridil/Topilutamide powder cas:260980-89-0
  • Non steroidal anti androgen Fluridil/Topilutamide powder cas:260980-89-0
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Non steroidal anti androgen Fluridil/Topilutamide powder cas:260980-89-0
  • Wuhan Hengheda Pharm Co.,Ltd
  • China
  • Immediately after payment
  • 10kg/month

Direct manufacture
Bulk quantity
Min 99 %
Free samples

Topilutamide

treatment of alopecia


Product Name

Topilutamide; Fluridil

Other Name

PropanaMide,2-hydroxy-2-Methyl-N-[4-nitro-3-(trifluoroMethyl)phenyl]-3-[(2,2,2-trifluoroacetyl)aMino

CAS No.

260980-89-0

Appearance

White powders

Purity

99%

MF

C13H11F6N3O5

Storage

Store at -20°C

Shelf Life

2 years

Usage

Research use only!


hair loss treatment

 

Topilutamide is a topical nonsteroidal antiandrogen (NSAA).Topilutamide downregulated androgen receptor expression by 40% at 3 uM and up to 95% at 10 uM in LNCaP Cells After 48-h drug incubation. While highly hydrophobic and hydrolytically degradable, it is systemically nonresorbable. In animals, fluridil demonstrated high local and general tolerance. After 3 months of topical application of topilutamide, the average anagen percentage did not change in placebo subjects but increased in topilutamide subjects (male with androgenetic alopecia) from 76% to 85%, and at 9 months to 87%. In former placebo subjects, topilutamide increased the anagen percentage after 6 months from 76% to 85%. Sexual functions, libido, hematology, and blood chemistry values were normal.




Topilutamide

treatment of alopecia

FAQ
Do we have the test reports for our products provided by the independent third party?
Every batch of our product was tested by authorized independent third party, Analysis testing center, Shanghai branch, Chinese Academy of Science. We send goods to customers with test report and COA. Our products were also tested by American Analytical Chemistry Laboratories and Chromadex too....more
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