Senna Leaf extract
Brownish yellow powder
6%, 8%, 10%, 20%, 30% Senna glycosides
The active ingredient in senna leaves is called sennoside. This component molecule is converted by microorganisms in the colon into another substance, anthrone rhein, which has beneficial effects, stimulating colonic activity (which accelerates intestinal peristalsis and improves digestion) and increasing fluid secretion. The laxative effect of sennoside and its active metabolite anthrone Rhein are considered to inhibit the absorption of water and electrolyte by the large intestine, thereby increasing the volume and pressure of intestinal contents. It will stimulate the push tightening movement of the colon. In addition, the stimulating effect on the secretion of active chloride increases the content of intestinal water and electrolyte. These changes in the transport of active electrolyte depend on the calcium element on the slurry surface. The laxative effect of sennoside is partly through the stimulation of colonic fluid and electrolyte secretion, and the secretion ability is regulated by the stimulation of endogenous prostaglandin formation. Sennoside can be prepared into enema or suppository or mixed with stool softener or lumped fiber laxative to form a combined laxative.
